|
rs71641308
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs67340775
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs13201681
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs67381177
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs34662244
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs35952432
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs9261204
|
|
|
0.010 |
GeneticVariation |
BEFREE |
G allele of SNP rs9261204 was significantly associated with an increased risk of lung cancer when compared with A allele (OR: 1.45; 95% CI: 1.19-1.75; P = 1.06 × 10-4).
|
27166266 |
2016 |
|
rs3757328
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNP rs3757328 was also associated with increased risk of lung cancer (OR: 1.34; 95% CI: 1.07-1.67; P = 0.011).
|
27166266 |
2016 |
|
rs116480994
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs17723637
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two novel SNPs, rs6441286 and rs17723637, were identified for overall lung cancer risk.
|
29059373 |
2018 |
|
rs760943842
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Loss of TP53-DNA interaction induced by p.C135R in lung cancer.
|
17914575 |
2007 |
|
rs115287935
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs149866169
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs1327135247
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The functional germline variant c.353T>C (p.Val118Ala) of Snai1 confers consistently decreased risks of lung cancer and COPD, and this variant affects lung cancer risk through a mediation effect of COPD.
|
24354880 |
2014 |
|
rs1487151044
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The functional germline variant c.353T>C (p.Val118Ala) of Snai1 confers consistently decreased risks of lung cancer and COPD, and this variant affects lung cancer risk through a mediation effect of COPD.
|
24354880 |
2014 |
|
rs3747093
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found a significant association between rs3747093 located in the CCDC116 promoter and lung cancer risk (OR = 0.91, P <sub>meta</sub> = 7.81 × 10<sup>-6</sup>).
|
28653172 |
2017 |
|
rs2131877
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the meta-analysis, rs2131877 at the chromosome 3q29 region was the most significant biomarker of lung cancer susceptibility in Koreans (P = 2.43 × 10(-8)).
|
20876614 |
2010 |
|
rs2025811
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We further showed that Xrn2 promotes proliferation and inhibits squamous differentiation in human lung epithelial cells and polymorphisms in human homolog XRN2 are associated with human lung cancer (rs2025811, P=1.90 x 10(-3), OR=1.20).
|
19915612 |
2010 |
|
rs132770
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this hospital-based case-control study, the association of XRCC6 promoter T-991C (rs5751129), promoter G-57C (rs2267437), promoter G-31A (rs132770), and intron 3 (rs132774) polymorphisms with lung cancer risk in a Taiwanese population, was studied.
|
22399625 |
2012 |
|
rs2267437
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this hospital-based case-control study, the association of XRCC6 promoter T-991C (rs5751129), promoter G-57C (rs2267437), promoter G-31A (rs132770), and intron 3 (rs132774) polymorphisms with lung cancer risk in a Taiwanese population, was studied.
|
22399625 |
2012 |
|
rs5751129
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this hospital-based case-control study, the association of XRCC6 promoter T-991C (rs5751129), promoter G-57C (rs2267437), promoter G-31A (rs132770), and intron 3 (rs132774) polymorphisms with lung cancer risk in a Taiwanese population, was studied.
|
22399625 |
2012 |
|
rs132774
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In this hospital-based case-control study, the association of XRCC6 promoter T-991C (rs5751129), promoter G-57C (rs2267437), promoter G-31A (rs132770), and intron 3 (rs132774) polymorphisms with lung cancer risk in a Taiwanese population, was studied.
|
22399625 |
2012 |
|
rs2075685
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In order to reveal the association between XRCC4 and lung cancer, we recruited 164 lung cancer patients and 649 healthy controls from central Taiwan, investigated seven novel polymorphic variants of XRCC4, includes C-1622T (rs7727691), G-1394T (rs6869366), G-652T (rs2075685), C-571T (rs2075686), intron3 DIP (rs28360071), S247A (rs3734091) and intron7 DIP (rs28360317), and analyzed the association of specific genotype with lung cancer susceptibility.
|
19729825 |
2009 |
|
rs2075685
|
|
|
0.020 |
GeneticVariation |
BEFREE |
It appeared that rs2075685, although associated with increased expression of a reporter gene and lung cancer risk in the Texas populations, did not have an effect on lung cancer risk in other populations.
|
21296624 |
2011 |
|
rs6869366
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In addition, significant association was maintained in prostate cancer (rs28360071), lung cancer (rs6869366) and bladder cancer (rs1805377) subgroups analysis.
|
23321468 |
2013 |